Too much paracetamol = dangerous because of how your liver processes it. *Normal dose:* About 90 95% gets broken down safely by glucuronidation + sulfation non toxic stuff you pee out. *The problem Combination of Paracetamol and the Glutathione Depleting Agent Buthionine Sulfoximine Show Differential Effect on Liver Cancer Cells and Normal Hepatocytes Tylenol's Impact on Glutathione and Liver Damage Are some people at increased risk of paracetamol induced liver injury? A critical review of the literature European Journal of Clinical Pharmacology Springer Nature Link Molecular Modelling Analysis of the Metabolism of Paracetamol
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paracetamol and glutathione depletion Acetaminophen – metabolism