Frontiers Glutathione deficiency in the pathogenesis of SARS CoV 2 infection and its effects upon the host immune response in severe COVID 19 disease View of Acetaminophen, the missing anion gap in the patient with metabolic acidosis The Southwest journal of medicine Normal Dose Paracetamol in Muscular Dystrophy Patients is it Normal? A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010 Correct Answer: B. N acetylcysteine (NAC) Why is this High Yield? Acetaminophen (Paracetamol) is widely used, making toxicity a common ER presentation. 1. Mechanism of Toxicity: Acetaminophen is metabolized in the liver.